| Date, Time |
Home |
Visitor |
Boxscore/Location |
| Fri April 20, 2012, 6:00 pm | Sabres | Lightning | 3-9 | Summary |
| Sat April 21, 2012, 1:00 pm | Sabres | Capitals | 3-5 | Summary |
| Fri April 27, 2012, 9:00 pm | Capitals | Sabres | 3-2 | Summary |
| Sat April 28, 2012, 1:00 pm | Sabres | Avalanche | 0-6 | Summary |
| Fri May 04, 2012, 7:00 pm | Lightning | Sabres | 7-5 | Summary |
| Sat May 05, 2012, 12:00 pm | Sabres | Capitals | 4-6 | Summary |
| Sun May 13, 2012, 5:00 pm | Avalanche | Sabres | 0-2 DEF | Summary |
| Fri May 25, 2012, 8:00 pm | Sabres | Lightning | 2-5 | Summary |
| Sat May 26, 2012, 9:00 am | Capitals | Sabres | 7-1 | Summary |
| Fri June 01, 2012, 7:00 pm | Sabres | Avalanche | 1-3 | Summary |
| Sat June 02, 2012, 4:00 pm | Lightning | Sabres | 5-2 | Summary |
| Sat June 09, 2012, 1:00 pm | Sabres | Capitals | 1-3 | Summary |
| Sun June 10, 2012, 3:00 pm | Avalanche | Sabres | 3-3 | Summary |
| Fri June 15, 2012, 8:00 pm | Sabres | Lightning | 4-6 | Summary |
| Sat June 16, 2012, 10:00 am | Lightning | Sabres | 3-2 OT | Summary |
| Sat June 23, 2012, 5:00 pm | Avalanche | Sabres | 2-3 OT | Summary |
