| Date, Time |
Home |
Visitor |
Boxscore/Location |
| Fri Apr 22, 2022, 8:00 pm | Liberty Vikings Hamilton | Pick Up Artists | 2-2 | Summary |
| Fri Apr 22, 2022, 8:00 pm | London Flamingos | Wolfpack Barrie | 2-2 | Summary |
| Fri Apr 22, 2022, 9:00 pm | Greenwood Knights | Niagara Spitfires | 5-5 | Summary |
| Fri Apr 22, 2022, 9:00 pm | Wolves Tillsonburg | Warriors Niagara | 1-1 | Summary |
| Fri Apr 22, 2022, 10:00 pm | Jaguars Niagara | Saints Vaughan | 0-2 | Summary |
| Fri Apr 22, 2022, 10:00 pm | Canadians Durham | Hamilton Knights | 3-5 | Summary |
| Sat Apr 23, 2022, 9:00 am | Liberty Vikings Hamilton | Niagara Spitfires | 0-2 | Summary |
| Sat Apr 23, 2022, 9:00 am | Greenwood Knights | Pick Up Artists | 3-3 | Summary |
| Sat Apr 23, 2022, 10:00 am | Wolves Tillsonburg | Wolfpack Barrie | 2-2 | Summary |
| Sat Apr 23, 2022, 10:00 am | London Flamingos | Warriors Niagara | 2-4 | Summary |
| Sat Apr 23, 2022, 11:00 am | Canadians Durham | Saints Vaughan | 4-6 | Summary |
| Sat Apr 23, 2022, 11:00 am | Jaguars Niagara | Hamilton Knights | 1-5 | Summary |
| Sat Apr 23, 2022, 1:00 pm | Warriors Niagara | Wolfpack Barrie | 2-2 | Summary |
| Sat Apr 23, 2022, 1:00 pm | Pick Up Artists | Niagara Spitfires | 1-2 | Summary |
| Sat Apr 23, 2022, 2:30 pm | London Flamingos | Wolves Tillsonburg | 2-2 | Summary |
| Sat Apr 23, 2022, 2:30 pm | Greenwood Knights | Liberty Vikings Hamilton | 1-3 | Summary |
| Sat Apr 23, 2022, 3:30 pm | Hamilton Knights | Saints Vaughan | 1-3 | Summary |
| Sat Apr 23, 2022, 3:30 pm | Jaguars Niagara | Canadians Durham | 1-5 | Summary |
| play-off | Sat Apr 23, 2022, 8:00 pm | Canadians Durham (8) | Saints Vaughan (1) | 4-1 | Summary |
| play-off | Sat Apr 23, 2022, 8:00 pm | Wolves Tillsonburg (7) | Niagara Spitfires (2) | 3-1 | Summary |
| play-off | Sat Apr 23, 2022, 9:00 pm | Wolfpack Barrie (6) | Hamilton Knights (3) | 4-3 | Summary |
| play-off | Sat Apr 23, 2022, 9:00 pm | Liberty Vikings Hamilton (5) | Warriors Niagara (4) | 4-0 | Summary |
| play-off | Sun Apr 24, 2022, 10:00 am | Canadians Durham (8) | Liberty Vikings Hamilton (5) | 4-2 | Summary |
| play-off | Sun Apr 24, 2022, 10:00 am | Wolves Tillsonburg (7) | Wolfpack Barrie (6) | 6-2 | Summary |
| play-off | Sun Apr 24, 2022, 1:30 pm | Canadians Durham (8) | Wolves Tillsonburg (7) | 3-1 | Summary |
